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Renova
Paracetamol BP
Description Paracetamol (Renova") is a potent and fast acting antipyretic & mid analgesic together with some anti-inflammatory effects. Paracetamol is the most widely used popular domestic analgesic and antipyretic for adults and children with significantly less side effects at the recommended dose Mode of action: Analgesic effects are thought to be related to the inhibition of prostaglandin synthesis and antipyresis through action on the hypothalamic heat-regulating center
Pharmacokinetics: Paracetamol is rapidly and completely absorbed aher oral administration with peak plasma concentration occuring between 15 mins and 2 hrs after ingestion depending on the formulation The mean half-life is about 2-3 hrs, with a range of 1.5-3.0 hrs. Paracetamol is extensively metabolized in the liver Some 2-5% of a therapeutic dose of Paracetamol is excreted unchanged in the urine. Composition: Renova 500 mg Tablet: Each tablet contains 500 mg Paracetamol BP Ranova® XR
Tablet: Each extended release tablet contains 665 mg Paracetamol BP. Renova Syrup: Each 5 m
contains 120 mg Paracetamol BP Renova Suspension: Each 5 mi contains 120 mg Paracetamol BP
Renova Paediatric drops: Each mi contains 80 mg Paracetamol BP. Renova 60 mg Suppository: Each
suppository contains 60 mg Paracetamol BP Renova 125 mg Suppository. Each suppository contains
125 mg Paracetamol BP Renova 250 mg Suppository: Each suppository contains 250 mg Paracetamol
BP. Renova 500 mg Suppository: Each suppository contains 500 mg Paracetamol BP
Indications: Fever, common cold and influenza, headache, toothache, earache, myalgia, dysmenorrhea
neuralgia and sprains, back pain, post-operative pain, post-partum pain, post-vaccination pain and fever
of children, rheumatism and osteoarthritic pain.
Dosage & administration:
Dosage form
Age Adults
Tablet
XR Tablet
Suspension
Syrup
Adults
Dosing
1-2 tablets, every 4-6 hrs to a maximum of 4 gm daily Children 6-12 yrs 1 to 1 tablet, dose may be repeated every 4-6 hrs when necessary
Adults and children over 12 years
Up to 3 months
2 tablets, swallowed whole, every 8 hours
10 mg/kg body weight (reduce to 5 mg/kg if jaundiced), dose
may be repeated every 4-6 hrs when necessary
3 months to 1 yr 1/2 to 1 teaspoonful, dose may be repeated every 4-6 hrs when necessary
1 to 5 yrs
6 to 12 yrs
1 to 2 teaspoonful; dose may be repeated every 4-6 hrs when necessary 2 to 4 teaspoonful; dose may be repeated every 4-6 hrs when necessary
4 to 8 teaspoonful; dose may be repeated every 4-6 hrs when necessary
Do not exceed 4 doses in 24 hrs
60 mg as a single dose, repeated once after 6 hrs when necessary
125 to 250 mg, dose may be repeated every 6 hrs when necessary 250 to 500 mg: dose may be repeated every 6 hrs when necessary
500 mg to gm dose may be repeated every 8 hrs when necessary
Suppository
Children up to 1 yrs Children to 5 yrs
Children 6 to 12 yrs
Adults
Dosage form
40 mg 0.5 mg dose may be repeated very 80 mg 11 m doee may be repeated every 4 hy when necessary
when necessary
120 11.3 mg dose may be repeated my wh
140 mg mit ose may be r 240 mg dose may tempeated every 4 why
Do not exceed 4 doses in 24
Contraindications Known sensitivity to Paracetamo
Side effects: Side effects are rare with nausea, vomiting, anorexia & abdominal pan but skin rashes and acute pancreatitis are reported after prolonged use hepatic damage and less sequenty renal damage on acute overdose
Use in pregnancy & lactation Paracetamol crosses the placenta and appears in the breast milk, but this is widely used in pregnancy and lactation and no foetal adverse effects have been recorded at the Precautions: Paracetamol should be given with care in patients with impared renal & hepatic functions
recommended doses
and alcohol dependence
Drug Interactions: Alcohol, barbiturates, anticonvulsants and tricyclic antidepressants may increase hepatotoxicity of Paracetamol, particularly aher an overdose. The speed of absorption of Paracetamol may be increased by metoclopramide or domperidone. The anticoagulant effect of warfarine and other coumarins may be enhanced by prolonged regular use of Paracetamol with increased risk of bleeding
Storage: Store in a cool (Below 25° C temperature) and dry place protected from light Packaging
Renova 500 mg Tablet: Each carton contains 10X25 tablets in blister pack Renova XR Tablet: Each carton contains 30X8 tablets in blister pack
Renova 60 ml Syrup: Each carton contansa amber pet bome having 60 mi syrup Renova 100 ml Syrup: Each carton contains a amber pet bottle having 100 ml syrup Renova 60 mi Suspension: Each carton contains a amber pet bottle having 60 m suspension Renova 100 ml Suspension: Each carton contains a amber pet botte having 100 ml suspension Renova Paediatric drops: Each carton contains a bottle having 15 mi Paediatric drops Renova 60 mg Suppository: Each carton contains 5X2 suppositones in blister pack Renova 125 mg Suppository. Each carton contains 5X2 suppositones in blister pack Renova 250 mg Suppository: Each carton contains 5X2 suppositones in bilister pack Renova 500 mg Suppository: Each carton contains 5X2 suppositories in blister pack
Opsonin Pharma
Manufactured by Rupatal, Barshal, Bangladesh
Registered Trade Mark
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৳50.00
-
৳400.00
-
৳250.00
-
৳130.00
-
৳330.00
-
৳375.00