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PRESENTATION
Reconil Tablet: Each film coated tablet contains Hydroxychloroquine Sulphate BP 200 mg.
DESCRIPTION
Hydroxychloroquine Sulphate synthetically produced version of quinine. It acts as an immunosuppressant by inhibiting production of
rheumatoid and acute phase reactants. It also accumulates in white blood cells, stabilizing lysosomal membranes and inhibiting the
activity of many enzymes, including collagenase and the proteases that cause cartilage breakdown. It also acts by disrupting cell
walls of infected red blood cells and kills the developing parasites.
INDICATIONS
i) Acute and chronic rheumatoid arthritis,
ii) Systemic Lupus Erythematosus (SLE),
iii) Malaria
DOSAGE & ADMINISTRATION
Hydroxychloroquine Sulphate tablets are for oral administration and are taken with food to avoid stomach upset.
i) Acute and chronic rheumatoid arthritis: 400 to 600 mg daily. When good response is obtained (usually 4 to 8 weeks), dose can be
reduced to 50%.
ii) Systemic Lupus Erythematosus (SLE): 400 mg once or twice daily for several weeks or months depending on response of the
patients. Maintenance dose is 200 to 400 mg daily.
iii) Malaria: In adults, an initial dose of 800 mg followed by 400 mg in 6-8 hours and 400 mg on each of two consecutive days. For
children a total dose representing 25 mg/kg is administered in 3 days as follows. First dose: 10 mg base/kg (but not exceeding a
single dose of 620 mg base). Second dose: 5 mg base/kg (but not exceeding a single dose of 310 mg base) 6 hours after first dose.
Third dose: 5 mg base/kg 18 hours after second dose. Fourth dose: 5 mg base/kg 24 hours after third dose.
* Hydroxychloroquine Sulphate BP 200 mg equivalent to 155 mg of base.
SIDE EFFECTS
Generally Hydroxychloroquine Sulphate is well tolerated. However, few side effects like nausea, vomiting, stomach upset, loss of
appetite, diarrhea, tiredness, weakness or headache and visual problem may occur the first several days.
PRECAUTIONS
Children are especially sensitive to the 4-aminoquinoline compounds. Patients should be strongly warned to keep these drugs out of
the reach of children. Opthalmologic examination requires in every 12 months.
USE IN PREGNANCY & LACTATION
During pregnancy, this drug should be used only if clearly needed. Since small amounts of this medication are found in breast milk
consult your doctor before medication.
OVER DOSE
Symptoms of overdose consist of headache, drowsiness, visual disturbances, cardiovascular collapse, and convulsions, followed by
sudden and early respiratory and cardiac arrest. Gastric lavage until the stomach is completely emptied.
COMMERCIAL PACK
Reconil Tablet : Each box contains 3 blister strip of 10 tablets.
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৳50.00
-
৳400.00
-
৳250.00
-
৳130.00
-
৳330.00
-
৳375.00