Pantonix Tablet 20mg

Pantonix®

sopraze Pantoni) is chemically a novel subdued bendazole darivative, which suppresses these acid production by forming a ond stes of the Ha ATPase any system at the secrety surface of the gastric petal cat The easton of both basal and simulated gastric ad secretion respective of the stimulus. The binding to the HK-ATPase esus in furation of antsvory effed t persists than 24 hours Parton Panni) is quantitatively absorbed and boevalability does not change upon mutiple doing Pants Panto) tararely metabolized in the r dose is excreted as metabolites in urine the hund in feces and originates from bary

Pantones) indicated where success of acid secretion of therapeutic benefit Pantopre Pamono registered for the towing indi

Pantoprazole tablet & injection

Description

3. Treatment of cer resistant to H2 receptor antagona (HRA) tot ulcers induced by non-steroidal and-darmatory figs (NSAIDs)

5 Gential 0 bleeding from stress or applic & Eradication of Helicobacter pylon (in combination with antia)

7.Zotinger Elison syndrome

Prophylax for and aspiration syndrome during induction of anaesthe

Dosage and Administration

Delayed reinase tablet

The usual recommended adult oral dose is 40 mg given ance daly before breakfast The duration of therapy is ranging from 28 Duodenal Ulcers Pants 4 mg tablet, once daily 4 weeks Duodenal ulcer generally heals within 7 weeks Gaste ukers Partonix 40 mg tablet, once daily for toworks Car generally heals within 4 weeks Refur excphagitis Paronis 40 mg tablet, once daily for 4 weeks Reus esophagis generaty heals within 4 week sistant ar Pantonis 40 mg tablet, once daily for weeks w duced by NSAIDs Pantunix 40 mg tablet once daily in patents receiving condu NSADA GI bleeding from stress or a petic disses Usual adult and dosage, retured the dosage may be incased Edation of Helcobacter pytat therapy of Partons 40 mg twice daily in combination with appropriate ambicoc for one week achieved eradication rates of 30 100% Zodinger En y Pantonix 40 mg tablets per day. Once conbol of acid secretion has been achieved, the dose should be gradually reduced to the west affective dose that mantains ad con Prophylaxia tv ad aspration syndone during induction of anaesthesie 1 or 2 Pantons 40 mg tablet should be given the evening before surgery and

Duodenal ulcer gastre ulcer gastrointestinal lesions rey Hg blockers, Zonger on syndrome

40 mg per day ily

20-40 mg per day intravenously

A ready-to-use solution is prepared by injecting 10 m 0.9% Sodium Chionde intravenous infusion into the va ined within 12 hours and stored at 2-8 ing the dry powder. The resulting solution should be

Refux esophag

Intravenous Pantoprazole should be replaced with oral therapy as soon as possible

Preparation for Use

1 Pypoc ulcer diseases (PLD) 2 Gastre esophageal reflux diseases (GERD)

After preparation then should be

Symptomat verse effects Headache (1.3%) and danboes (1.5%) are the two commonest reported adverse events. K doet infuence renal, sardo respiratory endocrine cognitive or motor functions and no content change have been found in any biochemical or haematogical peremeters Peripheral adama occasionally been reported in female paliers Other effects may include abdominal zziness, naus epigas discomfort, fatulence, skin resp

Pregnancy & Lactation

wwing one has been reported with resped to Partopr

Partons delayed release tables are corbaindate

Precautions

But 20 and 4 in diese of PP) are se

with heated esophage and PUD on

Pregnant women Available studies have not found any risk to the fetu

Lactating mother. There are no data on the excretion of Pantoprazole in the breastmilk

Neonates & Children

No data are available on administration of Pantoprazol

No problems with Pantoprazole have been encountered in clinical use in the pallent

No dosage adjustment of Pantoprazole is require in patents with mid moderate or severe renal insufficiency or in elderly patients. No dosage adjustment is necessary in patients undergoing haemodialysis. No dosage adjustment is needed in patients with mid or moderate hepatic impment in hepatic orthosis is recommended that

Elder patient

Concurrant disasse

group

Pantoprazole is metaboled through the cytochrome P-450 system, and subsequently undergoes Phase I corpugation. Based on studes evaluating possiteractions of Pantoprazole with cher drugs metabolized by the cytochoneme P-450 systent, no dosage atustment is needed with concomitant use of the blowing g teophytine, antyme caffeine carbamazepine, dazepam, dickfenac, digcain, ethanol, glyburide, an oral contracepove levonorgestrel withinyl estradio metoprolo

Drug interactions

the dosing is reduced to every other day

nedore phenylon, or warfarin. There was also no interaction with concomitanty administered antacids There are no known symptoms of overdosage in humans. Since Pantoprazole is highly protein bound, is not readily dalytable. Apart from symptomatic and supportive

Overdosage

management no specific therapy is recommended

Storage

Do not store above 30°C. Keep away from light and out of the reach of children

Pantai 20 tablet Each box contains 7 AkAlu beater stripe of 14 tablets Pantoni 40 ablet Each box contains 7 Alu-Alu blister at of 14ablets

Panton 40 injection Pack of 1 vial containing 40 mg Pantoprazole accompanied by ampoule of 10 m 0.9% Sodium Chloride Pinjection for intre-enous

and one 10 materie disposable syringe

Commercial Pack

Manufactured by

Incepta Pharmaceuticals Ltd

Savar, Dhaka, Bangladesh

Registered Trademark