Nidocard Retard Tablet 2.6mg

Nidocard-Retard

Nitroglycerin USP

Nocard-etard-6,4: Each tablet contains Nitroglycerin USP 64mg Competion: Each tablet contains Nitroglycerin USP 2.6mg Pharmacology: Nitroglycerin forms free radical nitric oxide which activates guanylate ocasting in an increase of guanosine 35 monophosphate (cyclic GMP) in so mucle and other tissues. This evertually leads to dephosphorylation of the light chain of myosin, which regulates the contractile state in smooth muscle, resulting in

Nidocard-Retard-2.5

Uses:Nocard doeases

is indicated for the prophylaxis of angina pectoris due to coronary artery tis indicated for the supplementary treatment of heart failure refractory to Aptals and diuretic treatment it is not suitable for treating an attack that has already stated as the tablets will take too long to start working Dosage & administration: It should be individualized depending on the nitroglycerin

sestvty of the patient, the severity of illness and the occurrence of side effects Nidocard-Retard-2.6: Usual dosage: 1 tablet 2 times a day before meal (in the morning. at noon necessary the doses may be raised gradually 2 or 3 tablets 2 times daily Nidocard-Retard-6.4: One tablet twice daily. O as directed by the registered physician.

Contra indications:

Nitroglycerin is containdicated in patients with early myocardial intacto severe anaemia, increased intracranial pressure and those with a known persensitivity to Nitroglycerin. Precautions: Excessive use may lead to the development of tolerance. The drug should be used cautiously in patients with volume depletion or low systolic blood pressure.

Paptation

position

Side-effects: The tablets may cause side effects such as: Dizziness or light headedness, especially when getting up from a lying or sitting

Headache, especially at the beginning of the treatment. Fushing of the face.

Drug Interactions: Concomitant use of nitrates with alcohol, antihypertensives, neuroleptics and tricyclic anti-depressant may cause hypotension. Use in pregnancy and lactation: There is no evidence relating to the safety of nitrates in pregnancy and lactation. Nitrate should not be administered to pregnant women and

nursing mothers unless considered essential by the physician. Storage: Store below 30°C away from sunlight.

Packing:

Nidocard-Retard-2.6: Each box contains 4 x 14's tablets in blister pack. Nidocard-Retard-6.4: Each box contains 3 x 14's tablets in blister pack.

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