Nexum Capsule 20mg

Nexum

Esomeprazole

COMPOSITION

POSAGE & AUWSTRAT

Healing of Once daily

Take daily for 10 days

7000

500 mg

Twice daily for 10 dept

Panda pean and oed Short term of GERD 20 mg x 43mg once daily for weeks and within weeks for pacents who do not heal here an anal 4 weeks treatment may be considered Fons de teve compleny arwerks an additional weeks

of treatment may be considered

40 mg per day intravenously

Dundalke ke persions refactory to blockers

Toger hon yndone

20-40 mg per day intravenously

SPECIAL POPULATION

Asage adment recary Rendency No dosage adjustment as necessary. Hepatx insufficiency No douge adjustment is necessary in

patients with mad to moderate ver garment for patients with severe lives impairment a dose of 20 mg should not be exceeded Gender No dosage

DRECTION FOR USE OF IV UECTION

bonepale lyphiliced powder and 0.9% Sodium Chloride inyection is for intravenous adminstration only and must not be given by any other route

Esomeprale injection 40 ing should be given as a slow inavenous injection. The solution for Nejection is obtained by adding 5 mi 0.9% Sodium Chloride tion to the vial containing powder After reconstitution the injection should be given slowly over a period of at least 3 minutes. Use only freshly prepared The reconstituted solution may be stored at room temperature up to 30 for a maximum 12 hours. Half of the injection should be used when 20 mg

administered DIRECTION FOR USE OF IV INFUSION

Esomeprae NV 40 ing should be given as an intravenous infusion over a period of 10 to 30 minutes, Esomeprame should be reconstituted with 3d of

Sodium Chloride injection and further dued admind with 3% Debose Injection or 9% Sodium Olande tion or Lactated Ringer's injection to a final

The reconstituted solution may be stored at room temperature (up to 30 for a maximum 12 hours prior to dilution. The admind tion may

be stored at on temperature top to 3 and must be used within 12 hours when reconstuted with 2% Sodium Chloride Injection or Lactated Rangers nction and within 6 hours when reconstituted with 3% Detrose Injection

CONTRAINDICATION

Esomeprate is contraindicated in these patients who have known hipersensitivity to any othm components of the mulation PRECAUTION

Exclude the pensibility of malignancy when patic uks spected and before treatment for dyspepsia. When using in combination with antice to the

prescribing information of the respective antibiotics This drug should be used during pregnancy only the potential beneft pofies the potential nok to the fetus Esomeprazole ely to be exceed in huma

USE IN PREGNANCY AND LACTATION

a decon should be made whether to discontinue using or to discontinue the drug taking into account the importance of the drug to the mother. SIDE EFFECT

Side effects reported with Esomeprazole include headache, dianthea and abdominal pain Esomeprazole appears to be a selective inhibitor of the cytochrome P450 monooxygenase system, there may be an effect on hepatic clearance, but there have

DRUG INTERACTION

been no reports la date of clinically relevant interactions. There is some uncertainty over the effect of Esomeprazole on the oral combined contraceptive pil Farther assesment is currently underway Phyological changes similar to those found with Omeprazole are likely to take place because of the reduction in gastric and which is likely to influence the bacterial colonization of the stomach and duodenum and abo vitamin B12 absorption

STORAGE

Store a cool and dry place at a temperature below 30 C. Kad away from light. Keep out of the reach of children Nevum 20 Cape Each box comans to capsules in Al Aku ter pack Mesum 40 Capsule Each box comes 30 capsules in Alu Alister M40ction Each box contains one vid of hoped omeprazole 40 mg one ampoule of Sodum Chunde njection & one tere poter

HOW SUPPLIED :Pack.

Manufactured by

SQUARE PHARMACEUTICALS LTD.

Kaliakoir, Gazipur, Bangladesh.

Registered Trade Mark